Successful Treatment of Necrobiotic Xanthogranuloma With Intravenous Immunoglobulin
نویسندگان
چکیده
منابع مشابه
Successful treatment of necrobiotic xanthogranuloma with intravenous immunoglobulin.
BACKGROUND Necrobiotic xanthogranuloma (NXG) is a rare chronic disorder characterized by firm yellow to red-orange nodules and plaques affecting the face, abdomen, and extremities with the potential for systemic involvement. NXG has a close association with monoclonal gammopathies, and there is a predilection for the development of multiple myeloma. Treatment options are varied due to inconsist...
متن کاملPhysiopathology of necrobiotic xanthogranuloma with monoclonal gammopathy
RATIONALE Xanthomatosis associated with monoclonal gammopathy includes hyperlipidaemic xanthoma (HX), normolipidaemic xanthoma (NX) and necrobiotic xanthogranuloma (NXG). All three pathologies are characterized by skin or visceral lesions related to cholesterol accumulation, monoclonal immunoglobulin (MIg) and hypocomplementemia. The pathophysiology underlying NXG remains unknown although the i...
متن کاملAtypical Necrobiotic Xanthogranuloma Associated with Epidermodysplasia Verruciformis
Necrobiotic xanthogranuloma is a rare, idiopathic, and chronic systemic granulomatous disorder that is usually associated with paraproteinemia of the immunoglobulin (Ig)G kappa (κ) type. It is clinically characterized by yellowish red-to-brown indurated often ulcerating nodules or plaques that usually involve the periorbital regions of the elderly. We report an atypical case of NXG affecting on...
متن کاملSuccessful treatment of severe Kikuchi's disease with intravenous immunoglobulin.
Physical examination showed a palpable defect in the quadriceps tendons, inferior displacement of the patella (patella baja), proximal ecchymosis, and swelling. Evaluation of range of motion revealed complete loss of active knee extension. The diagnosis of bilateral simultaneous rupture of the quadriceps tendons was suspected and further confirmed by knee radiographs, showing inferior patellar ...
متن کامل[Necrobiotic xanthogranuloma. Differential diagnosis, treatment and systemic involvement. Case report].
CASE REPORT A 48-year-old male was referred to our hospital for further evaluation of eyelid edema with bilateral yellowish ulcerated nodules. Suspecting a xanthogranulomatosis, imaging tests and biopsy were performed with diagnosis of necrobiotic xanthogranuloma. IgG monoclonal gammapathy was diagnosed in a systemic study. Systemic corticosteroids and cyclosporine were initiated unsuccessfully...
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ژورنال
عنوان ژورنال: Archives of Dermatology
سال: 2010
ISSN: 0003-987X
DOI: 10.1001/archdermatol.2010.236